2023 head-to-head · Midsize Car

2023 Cadillac CT5 vs Mercedes-Benz E-Class

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,194/ year to fuel
27 MPG
✓ Cheaper to run
$2,279/ year to fuel
26 MPG

The 2023 Cadillac CT5 is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,194 a year to fuel (27 MPG), versus $2,279 for the 2023 Mercedes-Benz E-Class (26 MPG). That's roughly $84 a year, or about $422 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Cadillac CT5
  • Mercedes-Benz E-Class

Side by side

Cadillac CT5Mercedes-Benz E-Class
$2,194 Your annual fuel cost $2,279
27 MPG Combined efficiency 26 MPG
23 MPG City 23 MPG
33 MPG Highway 31 MPG
99 cu ft Passenger volume 98 cu ft
11 cu ft Cargo volume 13 cu ft
333 g/mi Tailpipe CO₂ (g/mi) 342 g/mi
5/10 EPA fuel economy score 5/10
5/10 EPA greenhouse gas score 5/10
Gas Powertrain Gas
Premium gasoline Fuel Premium gasoline
2.0L 4-cyl turbo Engine / motor 2.0L 4-cyl turbo
10-speed automatic Transmission 9-speed automatic
RWD Drivetrain RWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Cadillac CT5 vs Mercedes-Benz E-Class across model years

  • Cadillac CT5
  • Mercedes-Benz E-Class

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Mercedes-Benz E-Class has more cargo space (13 vs. 11 cu ft).

Among 50 2023 midsize cars, the Cadillac CT5 ranks 35th and the Mercedes-Benz E-Class 36th for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2023 Cadillac CT5 or the 2023 Mercedes-Benz E-Class?

Measured by cost to drive, the Cadillac CT5. The Cadillac CT5 is rated 27 MPG combined and the Mercedes-Benz E-Class 26 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2023 Cadillac CT5 vs. the Mercedes-Benz E-Class per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,194 for the Cadillac CT5 and $2,279 for the Mercedes-Benz E-Class.

Which has more cargo space?

The Mercedes-Benz E-Class, with 13 cu ft of luggage volume versus 11 cu ft (EPA interior volume index).

Cadillac CT5 vs Mercedes-Benz E-Class in other years

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