2021 head-to-head · Midsize Car
2021 Cadillac CT5 vs Lexus LS
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
The 2021 Cadillac CT5 is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,279 a year to fuel (26 MPG), versus $2,693 for the 2021 Lexus LS (22 MPG). That's roughly $414 a year, or about $2,072 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Cadillac CT5
- Lexus LS
Side by side
| Cadillac CT5 | Lexus LS | |
|---|---|---|
| $2,279 | Your annual fuel cost | $2,693 |
| 26 MPG | Combined efficiency | 22 MPG |
| 23 MPG | City | 18 MPG |
| 32 MPG | Highway | 29 MPG |
| 99 cu ft | Passenger volume | 99 cu ft |
| 13 cu ft | Cargo volume | 13 cu ft |
| 337 g/mi | Tailpipe CO₂ (g/mi) | 399 g/mi |
| 5/10 | EPA fuel economy score | 4/10 |
| 5/10 | EPA greenhouse gas score | 4/10 |
| Gas | Powertrain | Gas |
| Premium gasoline | Fuel | Premium gasoline |
| 2.0L 4-cyl turbo | Engine / motor | 3.4L 6-cyl turbo |
| 10-speed automatic | Transmission | 10-speed automatic |
| RWD | Drivetrain | RWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Cadillac CT5 vs Lexus LS across model years
- Cadillac CT5
- Lexus LS
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Among 54 2021 midsize cars, the Cadillac CT5 ranks 39th and the Lexus LS 46th for lowest fuel cost.
Frequently asked questions
Which is more fuel-efficient, the 2021 Cadillac CT5 or the 2021 Lexus LS?
Measured by cost to drive, the Cadillac CT5. The Cadillac CT5 is rated 26 MPG combined and the Lexus LS 22 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2021 Cadillac CT5 vs. the Lexus LS per year?
At 15,000 miles a year with $3.95/gal premium gas, about $2,279 for the Cadillac CT5 and $2,693 for the Lexus LS.
Cadillac CT5 vs Lexus LS in other years
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