2021 head-to-head · Midsize Car

2021 Audi A6 Hybrid vs Lexus LS

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,279/ year to fuel
26 MPG
✓ Cheaper to run
$2,693/ year to fuel
22 MPG

The 2021 Audi A6 Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,279 a year to fuel (26 MPG), versus $2,693 for the 2021 Lexus LS (22 MPG). That's roughly $414 a year, or about $2,072 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Audi A6 Hybrid
  • Lexus LS

Side by side

Audi A6 HybridLexus LS
$2,279 Your annual fuel cost $2,693
26 MPG Combined efficiency 22 MPG
23 MPG City 18 MPG
31 MPG Highway 29 MPG
99 cu ft Passenger volume 99 cu ft
14 cu ft Cargo volume 13 cu ft
341 g/mi Tailpipe CO₂ (g/mi) 399 g/mi
5/10 EPA fuel economy score 4/10
5/10 EPA greenhouse gas score 4/10
Hybrid Powertrain Gas
Premium gasoline Fuel Premium gasoline
2.0L 4-cyl turbo Engine / motor 3.4L 6-cyl turbo
7-speed dual-clutch Transmission 10-speed automatic
AWD Drivetrain RWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Audi A6 Hybrid vs Lexus LS across model years

  • Audi A6 Hybrid
  • Lexus LS

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Audi A6 Hybrid has more cargo space (14 vs. 13 cu ft).

Among 54 2021 midsize cars, the Audi A6 Hybrid ranks 38th and the Lexus LS 46th for lowest fuel cost.

The powertrains differ: the Audi A6 Hybrid is a full hybrid, while the Lexus LS is a conventional gas model.

Frequently asked questions

Which is more fuel-efficient, the 2021 Audi A6 Hybrid or the 2021 Lexus LS?

Measured by cost to drive, the Audi A6 Hybrid. The Audi A6 Hybrid is rated 26 MPG combined and the Lexus LS 22 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2021 Audi A6 Hybrid vs. the Lexus LS per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,279 for the Audi A6 Hybrid and $2,693 for the Lexus LS.

Which has more cargo space?

The Audi A6 Hybrid, with 14 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).

Audi A6 Hybrid vs Lexus LS in other years

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