2021 · Midsize Car · Gas

2021 Mercedes-Benz E-Class MPG & fuel economy

The 2021 Mercedes-Benz E-Class is a midsize car offered in 3 EPA-rated configurations. The most efficient version returns 25 MPG combined (22 city / 31 highway) on premium gasoline. Across the lineup, combined ratings range from 18 to 25 MPG. That's down 1 MPG from the 2020 model. Among 54 midsize cars rated for 2021, it ranks 40th for lowest fuel cost. At 15,000 miles a year with $3.95/gal premium gas, it costs about $2,370 a year to fuel.

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Combined 25 MPG 22 MPG city · 31 MPG hwy
Driving range — not published for this model
Your fuel cost $2,370 15,000 mi/yr · $15.80 per 100 mi
Class rank, 2021 #40 of 54 Midsize Cars by fuel cost

What will it cost you?

Your mileage and prices are saved and used across the site.

Fuel average

The 2021 Mercedes-Benz E-Class's fuel average is 10.6 km/L (9.4 L/100 km), or 25 MPG combined: 9.4 km/L in the city and 13.2 km/L on the highway.

MPGkm/LL/100 km
City229.410.7
Highway3113.27.6
Combined2510.69.4

How it ranks among 2021 Midsize Cars

Full class ranking →
  1. 1Tesla Model 3142 MPGe $640
  2. 2Hyundai Ioniq EV133 MPGe $686
  3. 3Toyota Prius Prime133 MPGe + 54 MPG $763
  4. 4Hyundai Ioniq Plug-in Hybrid119 MPGe + 52 MPG $815
  5. 5Nissan Leaf111 MPGe $821
  6. 40Mercedes-Benz E-Class25 MPG $2,370
  7. 54Honda Clarity68 MPGe $7,941
2021 E-ClassOther midsize carsClass median: $1,689/yr

Annual fuel cost at 15,000 miles and default prices; shorter bars cost less.

E-Class MPG across model years

Full history →

3 EPA-rated configurations

ConfigurationTypeCityHwyCombinedRangeYour cost / yr
RWD · 2.0L 4-cyl turbo · 9-speed automatic
E350
Gas 22 MPG 31 MPG 25 MPG — $2,370
4WD · 2.0L 4-cyl turbo · 9-speed automatic
E350 4matic
Gas 22 MPG 30 MPG 25 MPG — $2,370
4WD · 4.0L 8-cyl turbo · 9-speed automatic
AMG E63 S 4matic Plus
Gas 16 MPG 23 MPG 18 MPG — $3,292

Specs (most efficient configuration)

Fuel
Premium gasoline
Engine / motor
2.0L 4-cyl turbo
Transmission
9-speed automatic
Drivetrain
RWD
Passenger volume
98 cu ft
Cargo volume
13 cu ft
Tailpipe CO₂
349 g/mi
EPA fuel economy score
5/10
EPA greenhouse gas score
5/10

2021 Mercedes-Benz E-Class vs. rivals

Compare the 2021 E-Class

With any other car from any year, including other E-Class model years. Type a year to jump, e.g. "2015 Accord".

Same year, other powertrains: 2021 Mercedes-Benz E-Class Hybrid (26 MPG)

Frequently asked questions

What is the gas mileage of the 2021 Mercedes-Benz E-Class?

Up to 25 MPG combined (22 city / 31 highway); ratings range from 18 to 25 MPG depending on configuration.

What fuel does the 2021 Mercedes-Benz E-Class use?

Premium gasoline (premium is required or recommended by the manufacturer).

What is the fuel average in km/L for the 2021 Mercedes-Benz E-Class?

The 2021 Mercedes-Benz E-Class's fuel average is 10.6 km/L (9.4 L/100 km), or 25 MPG combined: 9.4 km/L in the city and 13.2 km/L on the highway.

How much does it cost to fuel the 2021 Mercedes-Benz E-Class per year?

About $2,370 at 15,000 miles a year with $3.95/gal premium gas, or $15.80 per 100 miles. Use the calculator on this page to plug in your own mileage and prices.

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