2021 · Midsize Car · Gas
2021 Mercedes-Benz E-Class MPG & fuel economy
The 2021 Mercedes-Benz E-Class is a midsize car offered in 3 EPA-rated configurations. The most efficient version returns 25 MPG combined (22 city / 31 highway) on premium gasoline. Across the lineup, combined ratings range from 18 to 25 MPG. That's down 1 MPG from the 2020 model. Among 54 midsize cars rated for 2021, it ranks 40th for lowest fuel cost. At 15,000 miles a year with $3.95/gal premium gas, it costs about $2,370 a year to fuel.
What will it cost you?
Your mileage and prices are saved and used across the site.
Fuel average
The 2021 Mercedes-Benz E-Class's fuel average is 10.6 km/L (9.4 L/100 km), or 25 MPG combined: 9.4 km/L in the city and 13.2 km/L on the highway.
| MPG | km/L | L/100 km | |
|---|---|---|---|
| City | 22 | 9.4 | 10.7 |
| Highway | 31 | 13.2 | 7.6 |
| Combined | 25 | 10.6 | 9.4 |
How it ranks among 2021 Midsize Cars
Full class ranking →Annual fuel cost at 15,000 miles and default prices; shorter bars cost less.
E-Class MPG across model years
Full history →3 EPA-rated configurations
| Configuration | Type | City | Hwy | Combined | Range | Your cost / yr |
|---|---|---|---|---|---|---|
| RWD · 2.0L 4-cyl turbo · 9-speed automatic E350 |
Gas | 22 MPG | 31 MPG | 25 MPG | — | $2,370 |
| 4WD · 2.0L 4-cyl turbo · 9-speed automatic E350 4matic |
Gas | 22 MPG | 30 MPG | 25 MPG | — | $2,370 |
| 4WD · 4.0L 8-cyl turbo · 9-speed automatic AMG E63 S 4matic Plus |
Gas | 16 MPG | 23 MPG | 18 MPG | — | $3,292 |
Specs (most efficient configuration)
- Fuel
- Premium gasoline
- Engine / motor
- 2.0L 4-cyl turbo
- Transmission
- 9-speed automatic
- Drivetrain
- RWD
- Passenger volume
- 98 cu ft
- Cargo volume
- 13 cu ft
- Tailpipe CO₂
- 349 g/mi
- EPA fuel economy score
- 5/10
- EPA greenhouse gas score
- 5/10
2021 Mercedes-Benz E-Class vs. rivals
Compare the 2021 E-Class
With any other car from any year, including other E-Class model years. Type a year to jump, e.g. "2015 Accord".
Same year, other powertrains: 2021 Mercedes-Benz E-Class Hybrid (26 MPG)
Frequently asked questions
What is the gas mileage of the 2021 Mercedes-Benz E-Class?
Up to 25 MPG combined (22 city / 31 highway); ratings range from 18 to 25 MPG depending on configuration.
What fuel does the 2021 Mercedes-Benz E-Class use?
Premium gasoline (premium is required or recommended by the manufacturer).
What is the fuel average in km/L for the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class's fuel average is 10.6 km/L (9.4 L/100 km), or 25 MPG combined: 9.4 km/L in the city and 13.2 km/L on the highway.
How much does it cost to fuel the 2021 Mercedes-Benz E-Class per year?
About $2,370 at 15,000 miles a year with $3.95/gal premium gas, or $15.80 per 100 miles. Use the calculator on this page to plug in your own mileage and prices.