2021 head-to-head · Midsize Car
2021 Audi RS vs Mercedes-Benz E-Class
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
The 2021 Mercedes-Benz E-Class is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,370 a year to fuel (25 MPG), versus $2,821 for the 2021 Audi RS (21 MPG). That's roughly $451 a year, or about $2,257 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Audi RS
- Mercedes-Benz E-Class
Side by side
| Audi RS | Mercedes-Benz E-Class | |
|---|---|---|
| $2,821 | Your annual fuel cost | $2,370 |
| 21 MPG | Combined efficiency | 25 MPG |
| 18 MPG | City | 22 MPG |
| 25 MPG | Highway | 31 MPG |
| 91 cu ft | Passenger volume | 98 cu ft |
| 22 cu ft | Cargo volume | 13 cu ft |
| 428 g/mi | Tailpipe CO₂ (g/mi) | 349 g/mi |
| 4/10 | EPA fuel economy score | 5/10 |
| 4/10 | EPA greenhouse gas score | 5/10 |
| Gas | Powertrain | Gas |
| Premium gasoline | Fuel | Premium gasoline |
| 2.9L 6-cyl turbo | Engine / motor | 2.0L 4-cyl turbo |
| 8-speed automatic | Transmission | 9-speed automatic |
| AWD | Drivetrain | RWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Audi RS vs Mercedes-Benz E-Class across model years
- Audi RS
- Mercedes-Benz E-Class
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Mercedes-Benz E-Class has more passenger space (98 vs. 91 cu ft); the Audi RS has more cargo space (22 vs. 13 cu ft).
Among 54 2021 midsize cars, the Audi RS ranks 49th and the Mercedes-Benz E-Class 40th for lowest fuel cost.
Frequently asked questions
Which is more fuel-efficient, the 2021 Audi RS or the 2021 Mercedes-Benz E-Class?
Measured by cost to drive, the Mercedes-Benz E-Class. The Audi RS is rated 21 MPG combined and the Mercedes-Benz E-Class 25 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2021 Audi RS vs. the Mercedes-Benz E-Class per year?
At 15,000 miles a year with $3.95/gal premium gas, about $2,821 for the Audi RS and $2,370 for the Mercedes-Benz E-Class.
Which has more cargo space?
The Audi RS, with 22 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).
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