2025 head-to-head · Large Car

2025 Genesis G80 vs Mercedes-Benz S-Class Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,469/ year to fuel
24 MPG
✓ Cheaper to run
$2,469/ year to fuel
24 MPG

On fuel costs these two are nearly tied. Driving 15,000 miles a year with $3.95/gal premium gas, the most efficient 2025 Genesis G80 (24 MPG) costs about $2,469 a year to fuel and the 2025 Mercedes-Benz S-Class Hybrid (24 MPG) about $2,469.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Genesis G80
  • Mercedes-Benz S-Class Hybrid

Side by side

Genesis G80Mercedes-Benz S-Class Hybrid
$2,469 Your annual fuel cost $2,469
24 MPG Combined efficiency 24 MPG
20 MPG City 21 MPG
29 MPG Highway 31 MPG
107 cu ft Passenger volume 112 cu ft
15 cu ft Cargo volume 13 cu ft
377 g/mi Tailpipe CO₂ (g/mi) 364 g/mi
5/10 EPA fuel economy score 5/10
5/10 EPA greenhouse gas score 5/10
Gas Powertrain Hybrid
Premium gasoline Fuel Premium gasoline
2.5L 4-cyl turbo Engine / motor 3.0L 6-cyl turbo
8-speed automatic Transmission 9-speed automatic
AWD Drivetrain AWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Genesis G80 vs Mercedes-Benz S-Class Hybrid across model years

  • Genesis G80
  • Mercedes-Benz S-Class Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Mercedes-Benz S-Class Hybrid has more passenger space (112 vs. 107 cu ft); the Genesis G80 has more cargo space (15 vs. 13 cu ft).

Among 25 2025 large cars, the Genesis G80 ranks 17th and the Mercedes-Benz S-Class Hybrid 16th for lowest fuel cost.

The powertrains differ: the Genesis G80 is a conventional gas model, while the Mercedes-Benz S-Class Hybrid is a full hybrid.

Frequently asked questions

How much does it cost to fuel the 2025 Genesis G80 vs. the Mercedes-Benz S-Class Hybrid per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,469 for the Genesis G80 and $2,469 for the Mercedes-Benz S-Class Hybrid.

Which has more cargo space?

The Genesis G80, with 15 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).

Genesis G80 vs Mercedes-Benz S-Class Hybrid in other years

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