2025 head-to-head · Large Car
2025 Audi S8 Hybrid vs Mercedes-Benz S-Class Hybrid
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
AWD · 4.0L 8-cyl turbo · 8-speed automatic · 18 MPG
The 2025 Mercedes-Benz S-Class Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,469 a year to fuel (24 MPG), versus $3,292 for the 2025 Audi S8 Hybrid (18 MPG). That's roughly $823 a year, or about $4,115 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Audi S8 Hybrid
- Mercedes-Benz S-Class Hybrid
Side by side
| Audi S8 Hybrid | Mercedes-Benz S-Class Hybrid | |
|---|---|---|
| $3,292 | Your annual fuel cost | $2,469 |
| 18 MPG | Combined efficiency | 24 MPG |
| 15 MPG | City | 21 MPG |
| 24 MPG | Highway | 31 MPG |
| 111 cu ft | Passenger volume | 112 cu ft |
| 13 cu ft | Cargo volume | 13 cu ft |
| 502 g/mi | Tailpipe CO₂ (g/mi) | 364 g/mi |
| 4/10 | EPA fuel economy score | 5/10 |
| 4/10 | EPA greenhouse gas score | 5/10 |
| Hybrid | Powertrain | Hybrid |
| Premium gasoline | Fuel | Premium gasoline |
| 4.0L 8-cyl turbo | Engine / motor | 3.0L 6-cyl turbo |
| 8-speed automatic | Transmission | 9-speed automatic |
| AWD | Drivetrain | AWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Audi S8 Hybrid vs Mercedes-Benz S-Class Hybrid across model years
- Audi S8 Hybrid
- Mercedes-Benz S-Class Hybrid
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Among 25 2025 large cars, the Audi S8 Hybrid ranks 22nd and the Mercedes-Benz S-Class Hybrid 16th for lowest fuel cost.
Frequently asked questions
Which is more fuel-efficient, the 2025 Audi S8 Hybrid or the 2025 Mercedes-Benz S-Class Hybrid?
Measured by cost to drive, the Mercedes-Benz S-Class Hybrid. The Audi S8 Hybrid is rated 18 MPG combined and the Mercedes-Benz S-Class Hybrid 24 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2025 Audi S8 Hybrid vs. the Mercedes-Benz S-Class Hybrid per year?
At 15,000 miles a year with $3.95/gal premium gas, about $3,292 for the Audi S8 Hybrid and $2,469 for the Mercedes-Benz S-Class Hybrid.
Audi S8 Hybrid vs Mercedes-Benz S-Class Hybrid in other years
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