2025 head-to-head · Midsize Car

2025 Audi RS vs Lexus LS

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,576/ year to fuel
23 MPG
✓ Cheaper to run
$2,693/ year to fuel
22 MPG

The 2025 Audi RS is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,576 a year to fuel (23 MPG), versus $2,693 for the 2025 Lexus LS (22 MPG). That's roughly $117 a year, or about $585 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Audi RS
  • Lexus LS

Side by side

Audi RSLexus LS
$2,576 Your annual fuel cost $2,693
23 MPG Combined efficiency 22 MPG
20 MPG City 18 MPG
29 MPG Highway 29 MPG
87 cu ft Passenger volume 99 cu ft
8 cu ft Cargo volume 13 cu ft
385 g/mi Tailpipe CO₂ (g/mi) 404 g/mi
5/10 EPA fuel economy score 5/10
5/10 EPA greenhouse gas score 5/10
Gas Powertrain Gas
Premium gasoline Fuel Premium gasoline
2.5L 5-cyl turbo Engine / motor 3.4L 6-cyl turbo
7-speed dual-clutch Transmission 10-speed automatic
AWD Drivetrain RWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Audi RS vs Lexus LS across model years

  • Audi RS
  • Lexus LS

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Lexus LS has more passenger space (99 vs. 87 cu ft); the Lexus LS has more cargo space (13 vs. 8 cu ft).

Among 42 2025 midsize cars, the Audi RS ranks 36th and the Lexus LS 37th for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2025 Audi RS or the 2025 Lexus LS?

Measured by cost to drive, the Audi RS. The Audi RS is rated 23 MPG combined and the Lexus LS 22 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2025 Audi RS vs. the Lexus LS per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,576 for the Audi RS and $2,693 for the Lexus LS.

Which has more cargo space?

The Lexus LS, with 13 cu ft of luggage volume versus 8 cu ft (EPA interior volume index).

Audi RS vs Lexus LS in other years

More 2025 comparisons

Or compare the 2025 Audi RS with anything else:

Keep exploring