2025 head-to-head · Midsize Car
2025 Audi S6 Hybrid vs Lexus LS
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
AWD · 2.9L 6-cyl · 8-speed automatic · 22 MPG
On fuel costs these two are nearly tied. Driving 15,000 miles a year with $3.95/gal premium gas, the most efficient 2025 Audi S6 Hybrid (22 MPG) costs about $2,693 a year to fuel and the 2025 Lexus LS (22 MPG) about $2,693.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Audi S6 Hybrid
- Lexus LS
Side by side
| Audi S6 Hybrid | Lexus LS | |
|---|---|---|
| $2,693 | Your annual fuel cost | $2,693 |
| 22 MPG | Combined efficiency | 22 MPG |
| 19 MPG | City | 18 MPG |
| 27 MPG | Highway | 29 MPG |
| 99 cu ft | Passenger volume | 99 cu ft |
| 14 cu ft | Cargo volume | 13 cu ft |
| 408 g/mi | Tailpipe CO₂ (g/mi) | 404 g/mi |
| 5/10 | EPA fuel economy score | 5/10 |
| 5/10 | EPA greenhouse gas score | 5/10 |
| Hybrid | Powertrain | Gas |
| Premium gasoline | Fuel | Premium gasoline |
| 2.9L 6-cyl | Engine / motor | 3.4L 6-cyl turbo |
| 8-speed automatic | Transmission | 10-speed automatic |
| AWD | Drivetrain | RWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Audi S6 Hybrid vs Lexus LS across model years
- Audi S6 Hybrid
- Lexus LS
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Audi S6 Hybrid has more cargo space (14 vs. 13 cu ft).
Among 42 2025 midsize cars, the Audi S6 Hybrid ranks 38th and the Lexus LS 37th for lowest fuel cost.
The powertrains differ: the Audi S6 Hybrid is a full hybrid, while the Lexus LS is a conventional gas model.
Frequently asked questions
How much does it cost to fuel the 2025 Audi S6 Hybrid vs. the Lexus LS per year?
At 15,000 miles a year with $3.95/gal premium gas, about $2,693 for the Audi S6 Hybrid and $2,693 for the Lexus LS.
Which has more cargo space?
The Audi S6 Hybrid, with 14 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).
Audi S6 Hybrid vs Lexus LS in other years
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