2022 head-to-head · Large Car

2022 Audi A8 Hybrid vs Mercedes-Benz S-Class

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,693/ year to fuel
22 MPG

4WD · 3.0L 6-cyl turbo · 8-speed automatic · 22 MPG

✓ Cheaper to run
$3,950/ year to fuel
15 MPG

AWD · 6.0L 12-cyl turbo · 9-speed automatic · 15 MPG

The 2022 Audi A8 Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,693 a year to fuel (22 MPG), versus $3,950 for the 2022 Mercedes-Benz S-Class (15 MPG). That's roughly $1,257 a year, or about $6,284 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Audi A8 Hybrid
  • Mercedes-Benz S-Class

Side by side

Audi A8 HybridMercedes-Benz S-Class
$2,693 Your annual fuel cost $3,950
22 MPG Combined efficiency 15 MPG
19 MPG City 12 MPG
28 MPG Highway 21 MPG
111 cu ft Passenger volume 118 cu ft
13 cu ft Cargo volume 13 cu ft
399 g/mi Tailpipe CO₂ (g/mi) 599 g/mi
5/10 EPA fuel economy score 2/10
5/10 EPA greenhouse gas score 2/10
Hybrid Powertrain Gas
Premium gasoline Fuel Premium gasoline
3.0L 6-cyl turbo Engine / motor 6.0L 12-cyl turbo
8-speed automatic Transmission 9-speed automatic
4WD Drivetrain AWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Audi A8 Hybrid vs Mercedes-Benz S-Class across model years

  • Audi A8 Hybrid
  • Mercedes-Benz S-Class

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Mercedes-Benz S-Class has more passenger space (118 vs. 111 cu ft).

Among 29 2022 large cars, the Audi A8 Hybrid ranks 22nd and the Mercedes-Benz S-Class 27th for lowest fuel cost.

The powertrains differ: the Audi A8 Hybrid is a full hybrid, while the Mercedes-Benz S-Class is a conventional gas model.

Frequently asked questions

Which is more fuel-efficient, the 2022 Audi A8 Hybrid or the 2022 Mercedes-Benz S-Class?

Measured by cost to drive, the Audi A8 Hybrid. The Audi A8 Hybrid is rated 22 MPG combined and the Mercedes-Benz S-Class 15 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2022 Audi A8 Hybrid vs. the Mercedes-Benz S-Class per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,693 for the Audi A8 Hybrid and $3,950 for the Mercedes-Benz S-Class.

Audi A8 Hybrid vs Mercedes-Benz S-Class in other years

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