2022 head-to-head · Subcompact Car

2022 Audi A5 Hybrid vs Mercedes-Benz E-Class Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,043/ year to fuel
29 MPG
✓ Cheaper to run
$2,370/ year to fuel
25 MPG

The 2022 Audi A5 Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,043 a year to fuel (29 MPG), versus $2,370 for the 2022 Mercedes-Benz E-Class Hybrid (25 MPG). That's roughly $327 a year, or about $1,634 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Audi A5 Hybrid
  • Mercedes-Benz E-Class Hybrid

Side by side

Audi A5 HybridMercedes-Benz E-Class Hybrid
$2,043 Your annual fuel cost $2,370
29 MPG Combined efficiency 25 MPG
26 MPG City 23 MPG
34 MPG Highway 30 MPG
91 cu ft Passenger volume 98 cu ft
22 cu ft Cargo volume 13 cu ft
307 g/mi Tailpipe CO₂ (g/mi) 348 g/mi
6/10 EPA fuel economy score 5/10
6/10 EPA greenhouse gas score 5/10
Hybrid Powertrain Hybrid
Premium gasoline Fuel Premium gasoline
2.0L 4-cyl turbo Engine / motor 3.0L 6-cyl turbo
7-speed dual-clutch Transmission 9-speed automatic
AWD Drivetrain 4WD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Audi A5 Hybrid vs Mercedes-Benz E-Class Hybrid across model years

  • Audi A5 Hybrid
  • Mercedes-Benz E-Class Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Mercedes-Benz E-Class Hybrid has more passenger space (98 vs. 91 cu ft); the Audi A5 Hybrid has more cargo space (22 vs. 13 cu ft).

Among 34 2022 subcompact cars, the Audi A5 Hybrid ranks 7th and the Mercedes-Benz E-Class Hybrid 16th for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2022 Audi A5 Hybrid or the 2022 Mercedes-Benz E-Class Hybrid?

Measured by cost to drive, the Audi A5 Hybrid. The Audi A5 Hybrid is rated 29 MPG combined and the Mercedes-Benz E-Class Hybrid 25 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2022 Audi A5 Hybrid vs. the Mercedes-Benz E-Class Hybrid per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,043 for the Audi A5 Hybrid and $2,370 for the Mercedes-Benz E-Class Hybrid.

Which has more cargo space?

The Audi A5 Hybrid, with 22 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).

Audi A5 Hybrid vs Mercedes-Benz E-Class Hybrid in other years

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