2021 head-to-head · Compact Car

2021 Audi S4 vs Mercedes-Benz AMG GT Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,576/ year to fuel
23 MPG

AWD · 3.0L 6-cyl turbo · 8-speed automatic · 23 MPG

✓ Cheaper to run
$2,693/ year to fuel
22 MPG

4WD · 3.0L 6-cyl · 9-speed automatic · 22 MPG

The 2021 Audi S4 is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,576 a year to fuel (23 MPG), versus $2,693 for the 2021 Mercedes-Benz AMG GT Hybrid (22 MPG). That's roughly $117 a year, or about $585 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Audi S4
  • Mercedes-Benz AMG GT Hybrid

Side by side

Audi S4Mercedes-Benz AMG GT Hybrid
$2,576 Your annual fuel cost $2,693
23 MPG Combined efficiency 22 MPG
20 MPG City 20 MPG
28 MPG Highway 25 MPG
92 cu ft Passenger volume 96 cu ft
12 cu ft Cargo volume 13 cu ft
380 g/mi Tailpipe CO₂ (g/mi) 410 g/mi
5/10 EPA fuel economy score 4/10
5/10 EPA greenhouse gas score 4/10
Gas Powertrain Hybrid
Premium gasoline Fuel Premium gasoline
3.0L 6-cyl turbo Engine / motor 3.0L 6-cyl
8-speed automatic Transmission 9-speed automatic
AWD Drivetrain 4WD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Audi S4 vs Mercedes-Benz AMG GT Hybrid across model years

  • Audi S4
  • Mercedes-Benz AMG GT Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Mercedes-Benz AMG GT Hybrid has more passenger space (96 vs. 92 cu ft); the Mercedes-Benz AMG GT Hybrid has more cargo space (13 vs. 12 cu ft).

Among 37 2021 compact cars, the Audi S4 ranks 32nd and the Mercedes-Benz AMG GT Hybrid 34th for lowest fuel cost.

The powertrains differ: the Audi S4 is a conventional gas model, while the Mercedes-Benz AMG GT Hybrid is a full hybrid.

Frequently asked questions

Which is more fuel-efficient, the 2021 Audi S4 or the 2021 Mercedes-Benz AMG GT Hybrid?

Measured by cost to drive, the Audi S4. The Audi S4 is rated 23 MPG combined and the Mercedes-Benz AMG GT Hybrid 22 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2021 Audi S4 vs. the Mercedes-Benz AMG GT Hybrid per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,576 for the Audi S4 and $2,693 for the Mercedes-Benz AMG GT Hybrid.

Which has more cargo space?

The Mercedes-Benz AMG GT Hybrid, with 13 cu ft of luggage volume versus 12 cu ft (EPA interior volume index).

Audi S4 vs Mercedes-Benz AMG GT Hybrid in other years

More 2021 comparisons

Or compare the 2021 Audi S4 with anything else:

Keep exploring