2021 head-to-head · Compact Car
2021 Acura TLX vs Mercedes-Benz CLS-Class Hybrid
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
The 2021 Mercedes-Benz CLS-Class Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,279 a year to fuel (26 MPG), versus $2,370 for the 2021 Acura TLX (25 MPG). That's roughly $91 a year, or about $456 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Acura TLX
- Mercedes-Benz CLS-Class Hybrid
Side by side
| Acura TLX | Mercedes-Benz CLS-Class Hybrid | |
|---|---|---|
| $2,370 | Your annual fuel cost | $2,279 |
| 25 MPG | Combined efficiency | 26 MPG |
| 22 MPG | City | 23 MPG |
| 30 MPG | Highway | 30 MPG |
| 93 cu ft | Passenger volume | 93 cu ft |
| 14 cu ft | Cargo volume | 12 cu ft |
| 357 g/mi | Tailpipe CO₂ (g/mi) | 347 g/mi |
| 5/10 | EPA fuel economy score | 5/10 |
| 5/10 | EPA greenhouse gas score | 5/10 |
| Gas | Powertrain | Hybrid |
| Premium gasoline | Fuel | Premium gasoline |
| 2.0L 4-cyl turbo | Engine / motor | 3.0L 6-cyl turbo |
| 10-speed automatic | Transmission | 9-speed automatic |
| FWD | Drivetrain | RWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Acura TLX vs Mercedes-Benz CLS-Class Hybrid across model years
- Acura TLX
- Mercedes-Benz CLS-Class Hybrid
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Acura TLX has more cargo space (14 vs. 12 cu ft).
Among 37 2021 compact cars, the Acura TLX ranks 30th and the Mercedes-Benz CLS-Class Hybrid 28th for lowest fuel cost.
The powertrains differ: the Acura TLX is a conventional gas model, while the Mercedes-Benz CLS-Class Hybrid is a full hybrid.
Frequently asked questions
Which is more fuel-efficient, the 2021 Acura TLX or the 2021 Mercedes-Benz CLS-Class Hybrid?
Measured by cost to drive, the Mercedes-Benz CLS-Class Hybrid. The Acura TLX is rated 25 MPG combined and the Mercedes-Benz CLS-Class Hybrid 26 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2021 Acura TLX vs. the Mercedes-Benz CLS-Class Hybrid per year?
At 15,000 miles a year with $3.95/gal premium gas, about $2,370 for the Acura TLX and $2,279 for the Mercedes-Benz CLS-Class Hybrid.
Which has more cargo space?
The Acura TLX, with 14 cu ft of luggage volume versus 12 cu ft (EPA interior volume index).
Acura TLX vs Mercedes-Benz CLS-Class Hybrid in other years
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