2027 head-to-head · Midsize Car

2027 Audi A5 vs Mercedes-Benz E-Class Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,279/ year to fuel
26 MPG

AWD · 2.0L 4-cyl turbo · 7-speed dual-clutch · 26 MPG

✓ Cheaper to run
$2,116/ year to fuel
28 MPG

The 2027 Mercedes-Benz E-Class Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,116 a year to fuel (28 MPG), versus $2,279 for the 2027 Audi A5 (26 MPG). That's roughly $163 a year, or about $814 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Audi A5
  • Mercedes-Benz E-Class Hybrid

Side by side

Audi A5Mercedes-Benz E-Class Hybrid
$2,279 Your annual fuel cost $2,116
26 MPG Combined efficiency 28 MPG
22 MPG City 25 MPG
32 MPG Highway 33 MPG
96 cu ft Passenger volume 100 cu ft
23 cu ft Cargo volume 13 cu ft
345 g/mi Tailpipe CO₂ (g/mi) 316 g/mi
5/10 EPA fuel economy score 5/10
5/10 EPA greenhouse gas score 5/10
Gas Powertrain Hybrid
Premium gasoline Fuel Premium gasoline
2.0L 4-cyl turbo Engine / motor 2.0L 4-cyl turbo
7-speed dual-clutch Transmission 9-speed automatic
AWD Drivetrain RWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Audi A5 vs Mercedes-Benz E-Class Hybrid across model years

  • Audi A5
  • Mercedes-Benz E-Class Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Mercedes-Benz E-Class Hybrid has more passenger space (100 vs. 96 cu ft); the Audi A5 has more cargo space (23 vs. 13 cu ft).

Among 12 2027 midsize cars, the Audi A5 ranks 10th and the Mercedes-Benz E-Class Hybrid 9th for lowest fuel cost.

The powertrains differ: the Audi A5 is a conventional gas model, while the Mercedes-Benz E-Class Hybrid is a full hybrid.

Frequently asked questions

Which is more fuel-efficient, the 2027 Audi A5 or the 2027 Mercedes-Benz E-Class Hybrid?

Measured by cost to drive, the Mercedes-Benz E-Class Hybrid. The Audi A5 is rated 26 MPG combined and the Mercedes-Benz E-Class Hybrid 28 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2027 Audi A5 vs. the Mercedes-Benz E-Class Hybrid per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,279 for the Audi A5 and $2,116 for the Mercedes-Benz E-Class Hybrid.

Which has more cargo space?

The Audi A5, with 23 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).

Audi A5 vs Mercedes-Benz E-Class Hybrid in other years

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