2026 head-to-head · Large Car
2026 Mercedes-Benz S-Class vs Porsche Panamera
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
AWD · 6.0L 12-cyl turbo · 9-speed automatic · 15 MPG
The 2026 Porsche Panamera is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,821 a year to fuel (21 MPG), versus $3,950 for the 2026 Mercedes-Benz S-Class (15 MPG). That's roughly $1,129 a year, or about $5,643 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Mercedes-Benz S-Class
- Porsche Panamera
Side by side
| Mercedes-Benz S-Class | Porsche Panamera | |
|---|---|---|
| $3,950 | Your annual fuel cost | $2,821 |
| 15 MPG | Combined efficiency | 21 MPG |
| 12 MPG | City | 18 MPG |
| 20 MPG | Highway | 25 MPG |
| 115 cu ft | Passenger volume | 98 cu ft |
| 12 cu ft | Cargo volume | 27 cu ft |
| 603 g/mi | Tailpipe CO₂ (g/mi) | 431 g/mi |
| 2/10 | EPA fuel economy score | 4/10 |
| 2/10 | EPA greenhouse gas score | 4/10 |
| Gas | Powertrain | Gas |
| Premium gasoline | Fuel | Premium gasoline |
| 6.0L 12-cyl turbo | Engine / motor | 2.9L 6-cyl turbo |
| 9-speed automatic | Transmission | 8-speed dual-clutch |
| AWD | Drivetrain | RWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Mercedes-Benz S-Class vs Porsche Panamera across model years
- Mercedes-Benz S-Class
- Porsche Panamera
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Mercedes-Benz S-Class has more passenger space (115 vs. 98 cu ft); the Porsche Panamera has more cargo space (27 vs. 12 cu ft).
Among 24 2026 large cars, the Mercedes-Benz S-Class ranks 22nd and the Porsche Panamera 18th for lowest fuel cost.
Frequently asked questions
Which is more fuel-efficient, the 2026 Mercedes-Benz S-Class or the 2026 Porsche Panamera?
Measured by cost to drive, the Porsche Panamera. The Mercedes-Benz S-Class is rated 15 MPG combined and the Porsche Panamera 21 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2026 Mercedes-Benz S-Class vs. the Porsche Panamera per year?
At 15,000 miles a year with $3.95/gal premium gas, about $3,950 for the Mercedes-Benz S-Class and $2,821 for the Porsche Panamera.
Which has more cargo space?
The Porsche Panamera, with 27 cu ft of luggage volume versus 12 cu ft (EPA interior volume index).
Mercedes-Benz S-Class vs Porsche Panamera in other years
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