2026 head-to-head · Midsize Car

2026 Lexus ES Hybrid vs Mercedes-Benz E-Class Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$1,288/ year to fuel
46 MPG
✓ Cheaper to run
$2,116/ year to fuel
28 MPG

The 2026 Lexus ES Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $1,288 a year to fuel (46 MPG), versus $2,116 for the 2026 Mercedes-Benz E-Class Hybrid (28 MPG). That's roughly $828 a year, or about $4,140 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Lexus ES Hybrid
  • Mercedes-Benz E-Class Hybrid

Side by side

Lexus ES HybridMercedes-Benz E-Class Hybrid
$1,288 Your annual fuel cost $2,116
46 MPG Combined efficiency 28 MPG
48 MPG City 25 MPG
44 MPG Highway 33 MPG
101 cu ft Passenger volume 100 cu ft
13 cu ft Cargo volume 13 cu ft
191 g/mi Tailpipe CO₂ (g/mi) 316 g/mi
7/10 EPA fuel economy score 5/10
7/10 EPA greenhouse gas score 5/10
Hybrid Powertrain Hybrid
Premium gasoline Fuel Premium gasoline
2.5L 4-cyl Engine / motor 2.0L 4-cyl turbo
CVT Transmission 9-speed automatic
FWD Drivetrain RWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Lexus ES Hybrid vs Mercedes-Benz E-Class Hybrid across model years

  • Lexus ES Hybrid
  • Mercedes-Benz E-Class Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Among 31 2026 midsize cars, the Lexus ES Hybrid ranks 9th and the Mercedes-Benz E-Class Hybrid 20th for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2026 Lexus ES Hybrid or the 2026 Mercedes-Benz E-Class Hybrid?

Measured by cost to drive, the Lexus ES Hybrid. The Lexus ES Hybrid is rated 46 MPG combined and the Mercedes-Benz E-Class Hybrid 28 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2026 Lexus ES Hybrid vs. the Mercedes-Benz E-Class Hybrid per year?

At 15,000 miles a year with $3.95/gal premium gas, about $1,288 for the Lexus ES Hybrid and $2,116 for the Mercedes-Benz E-Class Hybrid.

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