2025 head-to-head · Midsize Car
2025 Lexus ES vs Mercedes-Benz E-Class Hybrid
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
The 2025 Lexus ES is the cheaper one to run. Driving 15,000 miles a year with $3.10/gal regular gas and $3.95/gal premium gas, it costs about $1,661 a year to fuel (28 MPG), versus $2,116 for the 2025 Mercedes-Benz E-Class Hybrid (28 MPG). That's roughly $455 a year, or about $2,277 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Lexus ES
- Mercedes-Benz E-Class Hybrid
Side by side
| Lexus ES | Mercedes-Benz E-Class Hybrid | |
|---|---|---|
| $1,661 | Your annual fuel cost | $2,116 |
| 28 MPG | Combined efficiency | 28 MPG |
| 24 MPG | City | 25 MPG |
| 33 MPG | Highway | 33 MPG |
| 97 cu ft | Passenger volume | 100 cu ft |
| 14 cu ft | Cargo volume | 13 cu ft |
| 320 g/mi | Tailpipe CO₂ (g/mi) | 316 g/mi |
| 6/10 | EPA fuel economy score | 6/10 |
| 6/10 | EPA greenhouse gas score | 6/10 |
| Gas | Powertrain | Hybrid |
| Regular gasoline | Fuel | Premium gasoline |
| 2.5L 4-cyl | Engine / motor | 2.0L 4-cyl turbo |
| 8-speed automatic | Transmission | 9-speed automatic |
| AWD | Drivetrain | RWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Lexus ES vs Mercedes-Benz E-Class Hybrid across model years
- Lexus ES
- Mercedes-Benz E-Class Hybrid
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Mercedes-Benz E-Class Hybrid has more passenger space (100 vs. 97 cu ft); the Lexus ES has more cargo space (14 vs. 13 cu ft).
Among 42 2025 midsize cars, the Lexus ES ranks 21st and the Mercedes-Benz E-Class Hybrid 26th for lowest fuel cost.
The powertrains differ: the Lexus ES is a conventional gas model, while the Mercedes-Benz E-Class Hybrid is a full hybrid.
Frequently asked questions
Which is more fuel-efficient, the 2025 Lexus ES or the 2025 Mercedes-Benz E-Class Hybrid?
Measured by cost to drive, the Lexus ES. The Lexus ES is rated 28 MPG combined and the Mercedes-Benz E-Class Hybrid 28 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2025 Lexus ES vs. the Mercedes-Benz E-Class Hybrid per year?
At 15,000 miles a year with $3.10/gal regular gas and $3.95/gal premium gas, about $1,661 for the Lexus ES and $2,116 for the Mercedes-Benz E-Class Hybrid.
Which has more cargo space?
The Lexus ES, with 14 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).
Lexus ES vs Mercedes-Benz E-Class Hybrid in other years
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