2025 head-to-head · Midsize Car
2025 Cadillac CT5 vs Lexus LS Hybrid
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
AWD · 3.5L 6-cyl · CVT · 25 MPG
The 2025 Cadillac CT5 is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,279 a year to fuel (26 MPG), versus $2,370 for the 2025 Lexus LS Hybrid (25 MPG). That's roughly $91 a year, or about $456 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Cadillac CT5
- Lexus LS Hybrid
Side by side
| Cadillac CT5 | Lexus LS Hybrid | |
|---|---|---|
| $2,279 | Your annual fuel cost | $2,370 |
| 26 MPG | Combined efficiency | 25 MPG |
| 23 MPG | City | 22 MPG |
| 32 MPG | Highway | 29 MPG |
| 99 cu ft | Passenger volume | 99 cu ft |
| 11 cu ft | Cargo volume | 12 cu ft |
| 341 g/mi | Tailpipe CO₂ (g/mi) | 358 g/mi |
| 5/10 | EPA fuel economy score | 5/10 |
| 5/10 | EPA greenhouse gas score | 5/10 |
| Gas | Powertrain | Hybrid |
| Premium gasoline | Fuel | Premium gasoline |
| 2.0L 4-cyl turbo | Engine / motor | 3.5L 6-cyl |
| 10-speed automatic | Transmission | CVT |
| RWD | Drivetrain | AWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Cadillac CT5 vs Lexus LS Hybrid across model years
- Cadillac CT5
- Lexus LS Hybrid
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Lexus LS Hybrid has more cargo space (12 vs. 11 cu ft).
Among 42 2025 midsize cars, the Cadillac CT5 ranks 32nd and the Lexus LS Hybrid 33rd for lowest fuel cost.
The powertrains differ: the Cadillac CT5 is a conventional gas model, while the Lexus LS Hybrid is a full hybrid.
Frequently asked questions
Which is more fuel-efficient, the 2025 Cadillac CT5 or the 2025 Lexus LS Hybrid?
Measured by cost to drive, the Cadillac CT5. The Cadillac CT5 is rated 26 MPG combined and the Lexus LS Hybrid 25 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2025 Cadillac CT5 vs. the Lexus LS Hybrid per year?
At 15,000 miles a year with $3.95/gal premium gas, about $2,279 for the Cadillac CT5 and $2,370 for the Lexus LS Hybrid.
Which has more cargo space?
The Lexus LS Hybrid, with 12 cu ft of luggage volume versus 11 cu ft (EPA interior volume index).
Cadillac CT5 vs Lexus LS Hybrid in other years
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