2025 head-to-head · Midsize Car
2025 Alfa Romeo Giulia vs Audi S5
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
The 2025 Alfa Romeo Giulia is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,194 a year to fuel (27 MPG), versus $2,576 for the 2025 Audi S5 (23 MPG). That's roughly $382 a year, or about $1,908 over five years.
Your numbers
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Fuel cost over 10 years
- Alfa Romeo Giulia
- Audi S5
Side by side
| Alfa Romeo Giulia | Audi S5 | |
|---|---|---|
| $2,194 | Your annual fuel cost | $2,576 |
| 27 MPG | Combined efficiency | 23 MPG |
| 24 MPG | City | 20 MPG |
| 33 MPG | Highway | 29 MPG |
| 100 cu ft | Passenger volume | 91 cu ft |
| 12 cu ft | Cargo volume | 22 cu ft |
| 330 g/mi | Tailpipe CO₂ (g/mi) | 384 g/mi |
| 5/10 | EPA fuel economy score | 5/10 |
| 5/10 | EPA greenhouse gas score | 5/10 |
| Gas | Powertrain | Gas |
| Premium gasoline | Fuel | Premium gasoline |
| 2.0L 4-cyl turbo | Engine / motor | 3.0L 6-cyl turbo |
| 8-speed automatic | Transmission | 8-speed automatic |
| RWD | Drivetrain | AWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Alfa Romeo Giulia vs Audi S5 across model years
- Alfa Romeo Giulia
- Audi S5
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Alfa Romeo Giulia has more passenger space (100 vs. 91 cu ft); the Audi S5 has more cargo space (22 vs. 12 cu ft).
Among 42 2025 midsize cars, the Alfa Romeo Giulia ranks 28th and the Audi S5 35th for lowest fuel cost.
Frequently asked questions
Which is more fuel-efficient, the 2025 Alfa Romeo Giulia or the 2025 Audi S5?
Measured by cost to drive, the Alfa Romeo Giulia. The Alfa Romeo Giulia is rated 27 MPG combined and the Audi S5 23 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2025 Alfa Romeo Giulia vs. the Audi S5 per year?
At 15,000 miles a year with $3.95/gal premium gas, about $2,194 for the Alfa Romeo Giulia and $2,576 for the Audi S5.
Which has more cargo space?
The Audi S5, with 22 cu ft of luggage volume versus 12 cu ft (EPA interior volume index).
Alfa Romeo Giulia vs Audi S5 in other years
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