2018 head-to-head · Compact Car

2018 Lexus IS vs Mercedes-Benz CLS-Class

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,279/ year to fuel
26 MPG
✓ Cheaper to run
$2,821/ year to fuel
21 MPG

The 2018 Lexus IS is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,279 a year to fuel (26 MPG), versus $2,821 for the 2018 Mercedes-Benz CLS-Class (21 MPG). That's roughly $543 a year, or about $2,713 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Lexus IS
  • Mercedes-Benz CLS-Class

Side by side

Lexus ISMercedes-Benz CLS-Class
$2,279 Your annual fuel cost $2,821
26 MPG Combined efficiency 21 MPG
22 MPG City 18 MPG
32 MPG Highway 26 MPG
90 cu ft Passenger volume 92 cu ft
11 cu ft Cargo volume 11 cu ft
345 g/mi Tailpipe CO₂ (g/mi) 425 g/mi
5/10 EPA fuel economy score 4/10
5/10 EPA greenhouse gas score 4/10
Gas Powertrain Gas
Premium gasoline Fuel Premium gasoline
2.0L 4-cyl turbo Engine / motor 4.7L 8-cyl turbo
8-speed automatic Transmission 9-speed automatic
RWD Drivetrain RWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Lexus IS vs Mercedes-Benz CLS-Class across model years

  • Lexus IS
  • Mercedes-Benz CLS-Class

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Among 44 2018 compact cars, the Lexus IS ranks 38th and the Mercedes-Benz CLS-Class 42nd for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2018 Lexus IS or the 2018 Mercedes-Benz CLS-Class?

Measured by cost to drive, the Lexus IS. The Lexus IS is rated 26 MPG combined and the Mercedes-Benz CLS-Class 21 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2018 Lexus IS vs. the Mercedes-Benz CLS-Class per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,279 for the Lexus IS and $2,821 for the Mercedes-Benz CLS-Class.

Lexus IS vs Mercedes-Benz CLS-Class in other years

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