2018 head-to-head · Midsize Car

2018 Audi A6 vs Mercedes-Benz E-Class

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,116/ year to fuel
28 MPG
✓ Cheaper to run
$2,370/ year to fuel
25 MPG

The 2018 Audi A6 is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,116 a year to fuel (28 MPG), versus $2,370 for the 2018 Mercedes-Benz E-Class (25 MPG). That's roughly $254 a year, or about $1,270 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Audi A6
  • Mercedes-Benz E-Class

Side by side

Audi A6Mercedes-Benz E-Class
$2,116 Your annual fuel cost $2,370
28 MPG Combined efficiency 25 MPG
25 MPG City 22 MPG
34 MPG Highway 30 MPG
98 cu ft Passenger volume 98 cu ft
16 cu ft Cargo volume 13 cu ft
311 g/mi Tailpipe CO₂ (g/mi) 351 g/mi
6/10 EPA fuel economy score 5/10
6/10 EPA greenhouse gas score 5/10
Gas Powertrain Gas
Premium gasoline Fuel Premium gasoline
2.0L 4-cyl turbo Engine / motor 2.0L 4-cyl turbo
7-speed dual-clutch Transmission 9-speed automatic
FWD Drivetrain RWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Audi A6 vs Mercedes-Benz E-Class across model years

  • Audi A6
  • Mercedes-Benz E-Class

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Audi A6 has more cargo space (16 vs. 13 cu ft).

Among 74 2018 midsize cars, the Audi A6 ranks 47th and the Mercedes-Benz E-Class 58th for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2018 Audi A6 or the 2018 Mercedes-Benz E-Class?

Measured by cost to drive, the Audi A6. The Audi A6 is rated 28 MPG combined and the Mercedes-Benz E-Class 25 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2018 Audi A6 vs. the Mercedes-Benz E-Class per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,116 for the Audi A6 and $2,370 for the Mercedes-Benz E-Class.

Which has more cargo space?

The Audi A6, with 16 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).

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